Question special

In the study, the ratio of peanut-specific IgG4 to IgE increased up to 30 months of age in the consumption group, and it was relatively constant in the peanut avoidance group. Currently, allergists do not commonly monitor IgG4 levels in clinical practice. How will IgG4 and IgE peanut be helpful in diagnosis and ongoing clinical management? Are they reliable markers? What is the role of monitoring IgG4 levels in our clinical practice?