As noted by one of the experts Dr. Howard Levy, there are still unknowns in mitochondria donation such as possible epigenetic consequences of utilizing a donor's cytoplasm. We will need long-term studies of recipients to understand epigenetic effects and learn how to prevent harm to future recipients. But does this mean unborn recipients must somehow consent to a lifetime of surveillance and follow-up? Is this too big a burden and too invasive for such research to be ethical? How can we mitigate intrusion into the lives of mitochondria recipients?
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