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Persistent post surgical pain is reported in 10%-50% of patients. Effective pain management requires multimodal and pre-emptive management strategies to relieve suffering, shorten hospital stay and reduce hospital costs. However, patient reported pain is highly subjective and persistent pain after an elective procedure (joint surgery) can leave patients feeling confused and cause mistrust in the doctor–patient relationship. Meditation can alleviate pain via reducing stress and anxiety, increasing mood-enhancing hormones and immune function. Using the MUSE device both pre and post operatively to learn, practice and improve meditative techniques could better manage post operative pain, reduce medication dependence and hospital stay time, and improve patient satisfaction. Data could be used to develop future “precision” pain medication protocols based on age, gender, and psychosocial status, improve the doctor–patient relationship and reduce healthcare dollars.