Question special
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Since the initial report of early goal-directed therapy (EGDT) being beneficial for the treatment of sepsis in 2001 (Rivers et al., PMID 11794169), has implementation of EGDT become widespread? Is the treatment of sepsis fairly consistent between institutions (as much as is possible considering the heterogeneous nature of sepsis and septic patients)? How should the results of these 3 recent trials change what is being taught?