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A question at the 'eleventh hour'...
It's really encouraging, Dr. Inge, to hear of intentions to follow up the whole TeenLABS cohort to at least 10 years.

But how long should the trials we are designing and delivering today follow up patients to appropriately investigate long-term and newer outcomes, such as bone fragility and cancers?

Even regarding adults, scepticism regarding the long-term potential negative consequences of bariatric/metabolic surgery still persists in substantial quarters, despite a mature literature base documenting outcomes in adults across several decades, some including impressively low loss to follow-up (e.g. SOS).

Is it feasible to follow adolescents across several decades?