Already in 2006 I have published (Med. Hypotheses 2006; 67:1266-1269) a hypothesis about transplantation of healthy "paternal" mitochondria into egg cells with diseased mitochondria. I realize that it will not be easy to remove diseased maternal mitochondria and next to transplant "paternal" mitochondria. However, it may prevent at least the juridical problem about the parents.
The mtDNA is very small as compared with the chromosomal DNA. The difference between healthy and severly diseased mitochondria in all body cells may nearly be compared with the difference between life and death. This makes that healthy mitochondria of the mitochondrion donor are extremely important in the new baby's life. As soon as a female mitochondrion donor of a 3-parents baby realizes her part in the new baby's life due to the role of mitochondria, problems may arise concerning deep maternal feelings, matrimonial ethics, matrimonial jurisdiction and rights of succession. At the moment the mitochondrion donor is part of the married couple, the new baby will be a 2-parents baby, and this might prevent many problems. What does the panel of experts think about this approach?
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