Hello and welcome to this NEJM discussion. My name is Phillip Romanski and I will be the lead moderator for this discussion. This article was a prospective trial comparing fresh day 3 embryo transfers to cryopreserved embryo transfers in 1508 infertile women with PCOS. The authors found that that the group randomized to frozen embryo transfer had a significantly higher frequency of live birth and lower frequency of pregnancy loss and ovarian hyper stimulation syndrome (OHSS). The frozen embryo group also had a higher rate of pre-eclampsia.
Before we get started, I would like to thank the authors of this paper for agreeing to participate in this open forum. Our hope is that all of the authors and experts on the panel will help to answer all of the questions that are submitted over the next 10 days, and I would encourage our panel to pose questions to the forum if they wish. All levels of questions are welcome.